This surprises most pet owners, including people who have had pets for decades.
Cats process certain compounds differently than dogs do, and pyrethroids and pyrethrins are the clearest example. The ASPCA Animal Poison Control Center documents cats as substantially more sensitive to pyrethroid exposure than dogs, to the point that products labeled for use on dogs can cause serious reactions in cats.
The practical implication is that “safe for pets” is not one category. A product selection appropriate for a household with a labrador may not be appropriate for a household with three cats, and the technician needs to know which situation they are walking into.
Cats also groom compulsively. Anything they pick up on their paws from a treated floor gets ingested during grooming, which is a route of exposure dogs have to a much lesser degree.

are highly sensitive to many insecticides. Aquariums should be covered with a solid lid and air pumps switched off during treatment and for a period afterward, since pumps draw airborne particles into the water.

have respiratory systems far more efficient than mammals at extracting compounds from air, which makes them correspondingly more vulnerable to airborne exposure. Cages should be moved to an untreated area, ideally out of the house during interior treatment.

in enclosures should be treated the same way as birds. Move them, or cover the enclosure and keep it out of the treatment zone.

Products are selected with safety in mind and applied according to professional standards. That selection should change based on what animals live there, particularly with cats.

This matters more than most homeowners realize. Gel bait placed directly into cockroach harborage inside a cabinet hinge is not on any surface a pet contacts. A perimeter barrier applied along the exterior foundation is outside the space pets occupy. Broadcast spraying across open floors puts material exactly where a dog lies down and a cat walks. UF/IFAS recommends integrated pest management, which selects the minimum effective treatment and applies it to specific locations rather than broadly across a property. Reduced pet exposure is a direct consequence of that approach rather than a separate feature.

Most residential products carry the greatest exposure risk while wet. Drying time varies by product and by conditions, and your technician should give you a specific window rather than a generic answer.

In homes with cats, wiping hard floors after the recommended re-entry period removes surface residue from the areas cats walk before grooming.

A company should be able to answer this specifically before the visit. Vague answers about industry-standard products are not transparency.

The answer should acknowledge the pyrethroid sensitivity difference. A company that says the treatment is identical either way has not thought about it.

Ask for a specific timeframe tied to the actual products, not a general rule.

Targeted placements into harborage areas carry a different exposure profile than surface spraying, and you are entitled to know which is happening.

Any reputable company provides this on request. Reluctance is informative.
Most of a South Florida pest control program happens outside, and that changes the exposure conversation.
Perimeter barrier treatment along the foundation, granular applications in landscape beds, and mosquito treatment of vegetation where adults rest all put material in areas pets may use. Dogs in particular spend time along fence lines and in landscape beds.
Keep pets indoors during exterior application and until treated surfaces have dried. Granular products in landscape beds warrant particular attention with dogs that dig or eat things off the ground.
Ask specifically about exterior re-entry timing rather than assuming interior guidance covers it.
No responsible pest control company should describe any treatment as completely safe or non-toxic. Those words are not accurate for products designed to affect living organisms, and a company using them is either being careless with language or being careless with your household.
The honest framing is that products are selected with safety in mind, applied in targeted locations, and paired with re-entry guidance that keeps exposure low. That is a real standard, and it is one you can hold a company to.
Anyone promising more than that is describing something the products do not do.
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